Cover Image

Volume 26, Issue 2

Pages: 129-209

February 2021


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Issue Information


Pages: 129-133 | First Published: 17 January 2021


Cover caption: Spirometry in a young patient with cystic fibrosis performed by Professor Graham Hall, Telethon Kids Institute and Curtin University, Perth, Australia (Photo credit: Telethon Kids Institute)

See Schneider et al. p147‐152.


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Assessing spirometry competency in community‐based settings: Bridging the gap between training and clinical practice

Paul Finlay CRFS, ACP

Pages: 134-135 | First Published: 14 December 2020

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The ongoing quest for a fountain of youth: Cell therapy for pulmonary fibrosis

Daniel C. Chambers MBBS, MRCP, FRACP, MD

Pages: 136-137 | First Published: 10 September 2020

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Endomicroscopy of the pleura highlights challenges and limitations of pleuroscopy

Y.C. Gary Lee MBChB, PhD, FCCP, FRCP, FRACP, Jenette Creaney PhD

Pages: 138-139 | First Published: 29 November 2020

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‘Surgery first’ if cure is your aim in CTEPH

Trevor J. Williams MBBS, MD, FRACP, David McGiffin MBBS, FRACS

Pages: 140-142 | First Published: 18 October 2020

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Social distancing as a strategy to prevent respiratory virus infections

Christine Jenkins AM, MD, FRACP, Anthony Sunjaya MD, SM

Pages: 143-144 | First Published: 15 December 2020

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Delayed access to lung cancer screening and treatment during the COVID‐19 pandemic: Are we headed for a lung cancer pandemic?

Tracy L. Leong MBBS (Hons), FRACP, MPH, PhD

Pages: 145-146 | First Published: 15 December 2020


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Assessing spirometry competence through certification in community‐based healthcare settings in Australia and New Zealand: A position paper of the Australian and New Zealand Society of Respiratory Science

Irene Schneider, Leanne Rodwell, Sarah Baum, Brigitte M. Borg, Eleonora A. Del Colle, Emily R. Ingram, Maureen Swanney, Deborah Taylor, ANZSRS Community‐Based Spirometry Competency Working Group

Pages: 147-152 | First Published: 14 December 2020


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Effects of roflumilast on arterial stiffness in COPD (ELASTIC): A randomized trial

Matthias H. Urban, Nicole Kreibich, Andreas Gleiss, Georg‐Christian Funk, Sylvia Hartl, Otto C. Burghuber

Pages: 153-160 | First Published: 28 July 2020


In this randomized controlled trial, roflumilast does not change markers of arterial stiffness or endothelial dysfunction after administration for 6 months in patients with stable COPD. We observed a significant and clinically important improvement in exercise capacity as a secondary end point.

Interstitial Lung Disease


Anti‐fibrotic effects of different sources of MSC in bleomycin‐induced lung fibrosis in C57BL6 male mice

Simone Periera‐Simon, Xiaomei Xia, Paola Catanuto, Ramon Coronado, Joanne Kurtzberg, Michael Bellio, Yee‐Shuan Lee, Aisha Khan, Robin Smith, Sharon J. Elliot, Marilyn K. Glassberg

Pages: 161-170 | First Published: 26 August 2020

MSC derived from adipose, chorion, villi and WJ were compared in their ability to rescue BLM‐induced lung fibrosis. Except for CSC, the fibrotic pathway activation was interrupted equally by all treatments; however, each source of MSC used a different mechanism to promote lung repair.

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Cause of mortality and sarcopenia in patients with idiopathic pulmonary fibrosis receiving antifibrotic therapy

Yuzo Suzuki, Yuya Aono, Masato Kono, Hirotsugu Hasegawa, Koushi Yokomura, Hyogo Naoi, Hironao Hozumi, Masato Karayama, Kazuki Furuhashi, Noriyuki Enomoto, Tomoyuki Fujisawa, Yutaro Nakamura, Naoki Inui, Hidenori Nakamura, Takafumi Suda

Pages: 171-179 | First Published: 23 September 2020


Skeletal muscle wasting (sarcopenia) without obvious weight loss is commonly found in patients with IPF receiving AFT. Most study patients died of chronic respiratory failure and skeletal muscle loss was associated with worse outcomes in AFT, suggesting that sarcopenia prevention is crucial for patients with IPF.

Lung Cancer


Risk of cancer incidence in patients with idiopathic pulmonary fibrosis: A nationwide cohort study

Hong Yeul Lee, Jinwoo Lee, Chang‐Hoon Lee, Kyungdo Han, Sun Mi Choi

Pages: 180-187 | First Published: 22 July 2020

This study revealed that patients with IPF have a higher cancer incidence risk than matched controls without IPF. Physicians should be aware of this risk when treating patients with IPF.

Pleural Disease

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Probe‐based confocal laser endomicroscopy for pleural malignancies diagnosis

Olivier Bonhomme, Vincent Heinen, Nancy Detrembleur, Jean‐Louis Corhay, Renaud Louis, Bernard Duysinx

Pages: 188-195 | First Published: 01 October 2020

Probe based confocal laser endomicroscopy (pCLE) is an optical imaging tool allowing live imaging of tissues at a cellular level. It remains experimental but its clinical value as a diagnostic/guiding tool is apparent. To address the lack of data in thoracic oncology and pleural diseases, we show the ability of pCLE during medical thoracoscopy to distinguish benign from malignant pleural involvement.

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Pulmonary Vascular Disease


Characteristics and long‐term survival of patients with chronic thromboembolic pulmonary hypertension in China

Limin Deng, Ruilin Quan, Yuanhua Yang, Zhenwen Yang, Hongyan Tian, Shengqing Li, Jieyan Shen, Yingqun Ji, Gangcheng Zhang, Caojin Zhang, Guangyi Wang, Yuhao Liu, Zhaozhong Cheng, Zaixin Yu, Zhiyuan Song, Zeqi Zheng, Wei Cui, Yucheng Chen, Shuang Liu, Changming Xiong, Guangliang Shan, Jianguo He

Pages: 196-203 | First Published: 20 September 2020

This is the first multicentre prospective registry reporting baseline characteristics and estimated survival of patients with chronic thromboembolic pulmonary hypertension (CTEPH) in China. A total of 593 patients with CTEPH were included. The long‐term survival rates are similar to those of patients in the international and Spanish registries. Pulmonary endarterectomy is an independent predictor of survival.

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Comparisons of early and late presentation to hospital in COVID‐19 patients

Sarah Williams, Natasha Sheard, Beth Stuart, Hang T.T. Phan, Florina Borca, Tom M.A. Wilkinson, Hannah Burke, Anna Freeman, on behalf of the REACT COVID Investigators

Pages: 204-205 | First Published: 06 December 2020


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Letter from Japan

Keiko Kan‐o MD, PhD

Pages: 206-207 | First Published: 02 December 2020

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Letter from Japan: Re‐thinking our future

Shu Hashimoto MD, PhD, Mari Hikichi MD, PhD, Shuichiro Maruoka MD, PhD, Yasuhiro Gon MD, PhD

Pages: 208-209 | First Published: 08 December 2020


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