Cover Image Respirology Case Reports
Volume 8, Issue 7

October 2020


Issue Information

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Issue Information

e00442 | First Published: 15 July 2020

Case Series

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Tracheobronchial amyloidosis: an uncommon disease with a common presentation
Loveleen Mangla, Rohit Vadala, Shirish Kumar Kadli, Deepak Prajapat, Deepak Talwar

e00630 | First Published: 02 August 2020


We describe three cases who presented with haemoptysis, which on further evaluation were diagnosed as isolated tracheobronchial amyloidosis, and a review of literature.

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Melioidosis—role of endobronchial ultrasound
Santhakumar Subramanian, Venugopal Jaganathan, Deepak T. Hari, Deepak Thangaraju

e00634 | First Published: 15 August 2020


Melioidosis is an emerging disease in India. Mediastinal abscess is rare in melioidosis. We have reported three such cases. Endobronchial ultrasound helped in diagnosis.

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Short‐course intrapleural alteplase and DNase in complex effusion with bleeding risk
Xiong Khee Cheong, Andrea Yu‐Lin Ban, Mohamed Faisal Abdul Hamid

e00648 | First Published: 25 August 2020


We described three patients with complex pleural effusions who received intrapleural fibrinolysis therapy with different bleeding risks.

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Thunderstorm‐related asthma can occur in New Zealand
Ayan Sabih, Claire Russell, Catherina L. Chang

e00655 | First Published: 31 August 2020


Thunderstorm asthma had previously been considered unlikely to occur in New Zealand (NZ), given its local weather patterns. Storm events on 2 December 2017 led to increased asthma presentations at Waikato Hospital in Hamilton. Analyses of patient presentations led us to conclude that these presentations were similar to international descriptions of thunderstorm asthma. This is the first time such presentations have been reported in NZ.

Case Reports

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A rare case of lung squamous cell carcinoma coexisting with pulmonary MALT lymphoma presenting as a progressive pGGN
Li Yang, Ting Wang, Mingjian Ge, Min Zhang, Youde Cao, Shuliang Guo

e00615 | First Published: 07 September 2020


Here, we present an extremely rare case of coexistence of lung squamous cell carcinoma with mucosa‐associated lymphoid tissue (MALT) lymphoma presenting as progressive lung ground‐glass nodules.

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Bronchial varices in a child with tricuspid atresia six years post Fontan correction
Shreya Bhushan, Vikas Goyal, Cameron Ward, Muddassir Rashid, Nitin Kapur

e00620 | First Published: 16 July 2020


Tracheal and bronchial varices are rare, especially in children. We report the first presentation of bronchial varices and haemoptysis in a child, six years after a Fontan procedure for tricuspid atresia. She had tortuous mediastinal and transpleural arterial collaterals on imaging and subsequently underwent embolization of these collaterals with haemoptysis settling after this.

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Indwelling pleural catheter and successful autopleurodesis of refractory inflammatory lupus effusion
Boon Hau Ng, Nik Nuratiqah Nik Abeed, Mohamed Faisal Abdul Hamid, Chun Ian Soo, Hsueh Jing Low, Andrea Yu‐Lin Ban

e00621 | First Published: 15 July 2020


Indwelling pleural catheter (IPC) is a useful tool for refractory malignant pleural effusions (MPEs). Its use in benign pleural effusions comes mainly from retrospective studies, case series, and case reports. Lupus effusion is common, causes minimal symptoms, and usually responds to either steroid therapy or immunosuppressants. We describe a 52‐year‐old woman whose first presentation of systemic lupus erythematosus (SLE) was a pleural effusion refractory to steroids and immunosuppressants. She successfully achieved spontaneous pleurodesis with intermittent IPC drainage at three months.

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A case of non‐severe COVID‐19 complicated by pulmonary embolism
Yuto Akiyama, Kohei Horiuchi, Yasushi Kondo, Hiroki Kabata, Makoto Ishii, Koichi Fukunaga

e00622 | First Published: 15 July 2020


Here, we report a case of non‐severe coronavirus disease 2019 (COVID‐19) complicated by pulmonary embolism (PE), which indicates that the possibility of PE should consistently be considered, even in non‐severe cases of COVID‐19 without any risk of thrombosis.

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Resolution of refractory chylothorax with a combination of talc pleurodesis and CPAP
Boon Hau Ng, Nik Nuratiqah Nik Abeed, Mohamed Faisal Abdul Hamid, Chun Ian Soo, Hsueh Jing Low, Andrea Yu‐Lin Ban

e00624 | First Published: 15 July 2020


We describe a 69‐year‐old woman with underlying diffuse large B‐cell lymphoma of the colon 16 years ago in remission, who presented with a new problem of refractory chylothorax. It was successfully treated with continuous positive airway pressure (CPAP) ventilation in tandem with talc pleurodesis.

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Advanced G‐CSF‐producing non‐small cell lung cancer‐not otherwise specified, with favourable response to pembrolizumab monotherapy
Yohei Matsui, Tadaaki Yamada, Naoko Masuzawa, Shinshichi Hamada, Koichi Takayama, Osamu Hiranuma

e00625 | First Published: 16 July 2020


Here, we report a patient with non‐small cell lung cancer‐not otherwise specified (NSCLC‐NOS) with high PD‐L1 expression and aberrant granulocyte colony‐stimulating factor (G‐CSF) production, in whom monotherapy with the anti‐PD‐1 antibody pembrolizumab was effective as an initial treatment.

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Bronchial mucoepidermoid carcinoma, recurrent asthmatic symptoms, and pneumonia presenting in pregnancy
Ritsuya Shiiba, Daisuke Himeji, Kiichiro Beppu, Kousuke Marutsuka, Masahiro Mitsuoka, Kazuki Nabeshima

e00626 | First Published: 05 August 2020


Here, we report the case of a 37‐year‐old pregnant Japanese woman with bronchial mucoepidermoid carcinoma, recurrent asthmatic symptoms, and pneumonia that we treated successfully via interventional bronchoscopy and surgery. At one‐year follow‐up, the patient was disease‐free and her baby was growing well.

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Incomplete metalloptysis linger pneumonia after a wedge resection of the lung for organizing pneumonia
Sen‐Ei Shai, Yi‐Ling Lai, Hsiao‐Wen Tang, Shih‐Chieh Hung

e00627 | First Published: 16 July 2020


We report the first case of incomplete metalloptysis linger pneumonia after the wedge resection of organizing pneumonia, with complete recovery by removal of residual clips, where clips from the staple cartridges had been applied on the periphery of the lung migrated and been incompletely expectorated.

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Thrombocytopaenia during nintedanib treatment in a patient with idiopathic pulmonary fibrosis
Yusuke Ochi, Motoyasu Kato, Masahiro Fujioka, Mika Hayashi, Haruhi Takagi, Kazuhisa Takahashi

e00628 | First Published: 16 July 2020


We present a rare case of symptomatic thrombocytopaenia associated with nintedanib treatment in a patient with idiopathic pulmonary fibrosis (IPF).

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De novo thymic carcinoma or malignant transformation: a myasthenic patient presented with multiple mediastinal tumours
Chu‐Pin Pai, Chih‐Ming Lin, Yi‐Chen Yeh, Chien‐Sheng Huang, Biing‐Shiun Huang

e00629 | First Published: 23 July 2020


Synchronous triple thymic carcinomas and thymoma have not been reported. The finding of this case report supports the hypothesis of malignant transformation of thymoma to thymic carcinoma.

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Haemorrhagic bronchial casts causing complete ventilatory failure in a COVID‐19 patient on ECMO
Samantha Herath, Natalie Kruit, Adam Eslick, Nicole Giroy

e00631 | First Published: 28 July 2020


We describe the surprise finding of haemorrhagic endobronchial casts causing complete ventilation failure in the first patient placed on extracorporeal membrane oxygenation (ECMO) for coronavirus disease 2019 (COVID‐19) in Australia. Removal of casts with international bronchoscopy procedures leads to the restoration of ventilation.

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Large cell carcinoma of the lung presenting as diffuse pulmonary infiltrates with haemoptysis
Gil Myeong Seong, Chang Lim Hyun, Jonggeun Lee, Changhwan Kim

e00632 | First Published: 31 July 2020


We report a case of large cell carcinoma identified during differential diagnosis of diffuse alveolar haemorrhage in a patient with haemoptysis.

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ABCA3 deficiency from birth to adulthood presenting as paediatric interstitial lung disease
Jin‐Gun Cho, Devesh Thakkar, Peter Buchanan, Nicole Graf, John Wheatley

e00633 | First Published: 07 August 2020


We describe the clinical progress of siblings who initially presented with an undifferentiated paediatric interstitial lung disease at birth which was eventually diagnosed in adulthood as pulmonary surfactant dysfunction due to ATP‐binding cassette subfamily A member 3 (ABCA3) mutations. Clinical deterioration was due to progressive pulmonary hypertension and a moderate decline in forced expiratory volume in 1 sec (FEV1), rather than progression of the interstitial lung disease.

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Solitary fibrous tumour of the pleura arising in a pulmonary cavity
Hiroyuki Miura, Jun Miura, Keisei Tachibana, Shinichi Goto

e00635 | First Published: 03 August 2020


Solitary fibrous tumour of the pleura (SFTP) is a rare neoplasm. Moreover, cavity formation associated with SFTP is extremely rare. To our knowledge, only one such case has been previously reported.

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Severe gastritis due to pembrolizumab treatment in a lung cancer patient
Noriko Hayama, Hiroaki Ihara, Yuichirou Honma, Yukinari Itoigawa, Kyoichi Kaira, Mitsuhiro Fujii

e00636 | First Published: 30 July 2020


The incidence of immune checkpoint inhibitor (ICI)‐induced gastritis is relatively rare, compared with colitis, but a massive immunoreaction caused by ICIs can induce severe gastritis. Thus, gastritis should be considered when patients taking ICIs complain of any gastrointestinal symptoms.


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